Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study
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The gut microbiota-derived Pathogen-Associated Molecular Patterns, including LPS and peptidoglycan, are recognized by Pattern Recognition Receptors (PRRs), in particular Toll-like receptors and NOD-like receptors, which are expressed on osteoclasts and osteoblasts (236)